{"id":202,"date":"2021-02-15T16:03:41","date_gmt":"2021-02-15T07:03:41","guid":{"rendered":"https:\/\/solaria.tokyo\/en?page_id=202"},"modified":"2024-03-08T11:13:24","modified_gmt":"2024-03-08T02:13:24","slug":"%e4%bf%ae%e5%be%a9%e5%8c%bb%e7%99%82%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6","status":"publish","type":"page","link":"https:\/\/solaria.tokyo\/en\/%e4%bf%ae%e5%be%a9%e5%8c%bb%e7%99%82%e3%81%ab%e3%81%a4%e3%81%84%e3%81%a6\/","title":{"rendered":"About regenerative medicine"},"content":{"rendered":"\r\n<p><span style=\"font-size: 12pt;\">Stem cell transplantation-based regenerative medicine is approaching a turning point with new methods. Stem cells are no longer the main actors; rather, it has been demonstrated in various studies that the liquid components produced by stem cells (SGF\u00ae) repair organs alongside one&#8217;s own stem cells.<\/span><\/p>\r\n<p><span style=\"font-size: 12pt;\">As a result, longstanding challenges associated with traditional stem cell transplantation, such as carcinogenesis, standardization, administration methods, shelf life, and cultivation methods, are being addressed. This has led to the emergence of a new field called &#8220;restorative medicine&#8221; facilitated by SGF\u00ae.<\/span><\/p>\r\n<p><span style=\"font-size: 12pt;\">In comparison to liver cell transplantation, SGF\u00ae is considered safer as it does not involve cell transplantation, reducing the risk of tumorigenesis.<\/span><\/p>\r\n<p><span style=\"font-size: 12pt;\">Furthermore, SGF\u00ae offers the advantage of using standardized quality products. Its potential for mass production and efficient administration methods allows for cost-effective utilization across a wide range of diseases. Administration methods include intravenous infusion, local administration, nasal sprays, etc., which are minimally invasive with minimal reported side effects.<\/span><\/p>\r\n<p style=\"font-size: 16px;\"><img loading=\"lazy\" decoding=\"async\" width=\"977\" height=\"738\" class=\"wp-image-1027\" style=\"font-size: 14px;\" src=\"https:\/\/solaria.tokyo\/en\/wp-content\/uploads\/2021\/05\/\u30d1\u30e9\u30af\u30e9\u30a4\u30f3\u30a8\u30d5\u30a7\u30af\u30c8.jpg\" alt=\"\" srcset=\"https:\/\/solaria.tokyo\/en\/wp-content\/uploads\/2021\/05\/\u30d1\u30e9\u30af\u30e9\u30a4\u30f3\u30a8\u30d5\u30a7\u30af\u30c8.jpg 977w, https:\/\/solaria.tokyo\/en\/wp-content\/uploads\/2021\/05\/\u30d1\u30e9\u30af\u30e9\u30a4\u30f3\u30a8\u30d5\u30a7\u30af\u30c8-300x227.jpg 300w, https:\/\/solaria.tokyo\/en\/wp-content\/uploads\/2021\/05\/\u30d1\u30e9\u30af\u30e9\u30a4\u30f3\u30a8\u30d5\u30a7\u30af\u30c8-768x580.jpg 768w\" sizes=\"(max-width: 977px) 100vw, 977px\" \/><\/p>\r\n\r\n\r\n\r\n<p style=\"font-size: 16px;\">Potentially, ASCs may lead to cardiac regeneration via different mechanisms. Transdifferentiation into newly formed cardiomyocytes has been the first proposed way. Cell fusion of stem cells with native cardiomyocytes represents a second possibility but the biological meaning of this event remains unclear. <span class=\"has-inline-color has-vivid-cyan-blue-color\">Finally, soluble paracrine factors released by the stem cells may induce activation, migration and differentiation of CSCs and\/or enhance proliferation of resident cardiomyocytes.Soluble paracrine factors released by stem cells may induce activation, migration, and differentiation of CSCs, and\/or enhance proliferation of resident myocardial cells.<\/span><\/p>\r\n\r\n\r\n\r\n<h3 class=\"wp-block-heading\" id=\"\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u75be\u60a3\">Diseases for which effects can be expected<\/h3>\r\n\r\n\r\n\r\n<ul style=\"font-size: 16px;\">\r\n<li>Diabetes<\/li>\r\n<li>Liver disease<\/li>\r\n<li>Kidney disease<\/li>\r\n<li>Atopic dermatitis<\/li>\r\n<li>Rheumatoid arthritis (joint pain)<\/li>\r\n<li>Erectile dysfunction (impotence)<\/li>\r\n<li>Vascular endothelial cell damage due to hypertension<\/li>\r\n<li>Osteoarthritis of the knee<\/li>\r\n<li>Sequelae of cerebral infarction<\/li>\r\n<\/ul>\r\n","protected":false},"excerpt":{"rendered":"Stem cell transplantation-based regenerative medicine is approaching a turning point with new methods. Stem ce [&hellip;]","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/solaria.tokyo\/en\/wp-json\/wp\/v2\/pages\/202"}],"collection":[{"href":"https:\/\/solaria.tokyo\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/solaria.tokyo\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/solaria.tokyo\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/solaria.tokyo\/en\/wp-json\/wp\/v2\/comments?post=202"}],"version-history":[{"count":11,"href":"https:\/\/solaria.tokyo\/en\/wp-json\/wp\/v2\/pages\/202\/revisions"}],"predecessor-version":[{"id":2138,"href":"https:\/\/solaria.tokyo\/en\/wp-json\/wp\/v2\/pages\/202\/revisions\/2138"}],"wp:attachment":[{"href":"https:\/\/solaria.tokyo\/en\/wp-json\/wp\/v2\/media?parent=202"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}