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How to overcome the barriers of standard cancer treatment.

Salaria Clinic Tokyo is a satellite clinic of the Edogawa Hospital, a social welfare corporation located in Edogawa Ward, Tokyo, specializing in cancer immunotherapy and precision medicine. Our facility focuses on addressing the challenge of surpassing the limitations of standard cancer treatment by harnessing our current maximum capabilities. Through our private medical services, Salaria Clinic Tokyo offers cancer treatment utilizing advanced therapies such as Super NK Therapy, which activates Granzyme β through our proprietary cultivation method, and NKT Cell Targeted Therapy, which activates NKT cells for treatment. Precision medicine, utilizing molecular-targeted drugs determined by the cancer\'s genetic profile, further enhances the efficacy of treatment beyond that of standard therapies. 

Who performs cancer treatment?

Along with Shoji Koga, the Vice Director of Edogawa Hospital and Director of Salaria Clinic Tokyo, and Tomohiro Myojoh, the Vice Director of Edogawa Hospital specializing in Precision Medicine, and Masajiro Kato, the Director of Edogawa Hospital, specialists collaborate to provide highly specialized treatment.

The general hospital provides backup.

The Edogawa Hospital, operated by the social welfare corporation Jinsei-sha, is a comprehensive hospital located in Edogawa Ward, with over 90 years of history. In cancer treatment, it has been utilizing advanced technologies and equipment since early on. Last year, it initiated physician-led specific clinical research such as BNCT (boron neutron capture therapy) and CT-guided (Tomotherapy) and MRI-guided (ViewRay system) high-precision radiation therapy. It is a core hospital in the region that focuses on reducing the loss of lives due to cancer by striving for early detection of difficult-to-find cancers.

What is precision medicine?

Precision medicine is a treatment method that identifies the fundamental causes of cancer through genetic testing and selects \"immunotherapy\" or \"targeted therapy\" based on genomic information. Conventional treatments mainly involve trying drugs believed to be effective based on past statistics, and it was not known whether they would be effective until they were administered to patients. Precision medicine can achieve highly effective treatment tailored to specific gene mutations that cause cancer.

Flow of treatment

 

Flow of treatment

現在の状態とこれまでの治療経緯をお伺いして、NKT細胞標的治療を行えるか同課の診断を行います。完全予約制になりますので、事前にお電話にてお問合せ頂けますようお願い致します。準備いただきたい資料等をご案内致します。

細胞培養に必要な感染症検査を行います。通常は初診時に実施可能であれば同日にて採血を行います。結果が出るまで1週間ほど要します。

NKT細胞標的治療のマーカーとなる免疫の状態を見る検査を行います。この免疫検査は、治療完了後再度同じ検査をして、比較しますが評価はこの検査の結果だけではなく、腫瘍マーカーや、CT画像等によって総合的に評価します。

血液から培養する細胞の元となる単球を取り出すため成分採血を行います。3時間から3.5時間ほど時間を要します。

採血完了後、直ちに培養施設に移送し、翌日から培養が開始されます。通常2週間程度で培養が完了し、当センター到着後直ちに投与日程の調整を行い、投与日を決定します。

αガルセルにより、加工された樹状細胞を4回に分けて投与します。投与は2週間に1度の頻度で行います。

NKT細胞標的治療のマーカーとなる免疫の状態を見る検査を行います。この免疫検査は、治療開始時と再度同じ検査をして、比較しますが評価はこの検査の結果だけではなく、腫瘍マーカーや、CT画像等によって総合的に評価します。

1クール4回の投与が完了した後、3週間~1か月後に再度免疫検査を行い、結果が出た後に診察を行います。治療の評価により今後について相談します。